Department of Health Research, Ministry of Health and Family Welfare, Government of India
स्वास्थ्य अनुसंधान विभाग, स्वास्थ्य और परिवार कल्याण मंत्रालय, भारत सरकार
WHO Collaborating Centre For Research and Training On Diarrhoeal Diseases
Name | Dr. Moumita Dutta |
---|---|
Designation | Scientist C |
Date of joining ICMR | 01 December 2017 |
Date of joining present post | 01 December 2017 |
Discipline | Electron Microscopy |
Division | |
Specialization | |
Email : | mdutta16@gmail.com ; moumita.dutta@icmr.gov.in |
Academic Qualification | |
Graduation | Chemistry(H) (University of Calcutta) |
Post Graduation | Biochemistry (University of Calcutta) |
Doctoral | NICED/Jadavpur University (Characterization of Choleraphages using Electron Microscopy). . |
I have several years of research experience on various
electron microscopic techniques: negative staining, cryo-electron
microscopy, single particle analysis, cryo-electron
tomography, immune-electron microscopy, ultramicrotomy,
Kleinschmidt's protein monolayer technique, and partial
denaturation mapping of DNA. I have worked as a
postdoctoral research associate at Florida State
University (USA) on HIV/SIV glycoprotein spikes and
their complexes with broadly neutralizing antibodies
using cryo-electron tomography and subtomogram averaging
to provide structural information for designing better
immunogen. I have also worked on structural
intermediates of the bacterial replication initiation
process and retroviral capsid structures using cryo-electron
tomography as a career development fellow at Francis
Crick Institute, London. Later I worked as a senior
staff scientist in cryo-electron microscopy at the
University of Sheffield, UK. Since my joining at NICED,
my laboratory is working on enteric bacteriophages and
their characterization by biophysical and structural
methods...
My research interest focuses on studying enteric bacteriophages and their three-dimensional structure determination. Another research area is the enveloped viruses and associated membrane proteins to understand the structure-function relation and fundamental processes such as host-virus interaction and viral entry. I am also interested in structural analysis of protein and their complexes, immune-complexes to explain their functions in biological processes and related diseases. Surface structural changes and in-depth ultrastructural changes caused by different enteric pathogens are also studied in our division by scanning and transmission electron microscopy techniques. Bacteriophage-host bacteria interactions are studies at high-resolution using a cutting-edge technique cryo-electron microscopy and tomography along with image processing techniques.
Students (Please include names of students presently working in the lab)
JRF : Payel Mondal (CSIR)
SRF : Bani Mallick (UGC)