Department of Health Research, Ministry of Health and Family Welfare, Government of India
स्वास्थ्य अनुसंधान विभाग, स्वास्थ्य और परिवार कल्याण मंत्रालय, भारत सरकार
WHO Collaborating Centre For Research and Training On Diarrhoeal Diseases
Dr. Nilanjan Chakraborty is Scientist in the ICMR institute, National Institute of Cholera and Enteric Diseases (NICED), Kolkata working in the field of virology for over a decade. Dr. Chakraborty has work experiences in the fields of microbiology and virology. He graduated in 1984, gained his Masters in Botany with Microbiology in 1987 from Kalyani University, and did his Ph. D. from Kalyani University in 1995. He joined ICMR Virus Unit, Kolkata as Scientist C in the year 2003 and his current position is Scientist E in the virus research laboratory of NICED.
Upon joining Virus Unit, Dr. Chakraborty committed himself on learning the distribution of different opportunistic infections prevalent among the HIV infected patient groups of Eastern India. Furthermore, he extended the work to deduce the drug susceptibility profile of Mycobacterium tuberculosis isolated from HIV-infected and uninfected Pulmonary Tuberculosis patients which provided some significant observations regarding the prevalence and rise of XDR-TB and MDR-TB strains in Eastern India. His research to apprehend the frequency of multiple herpes virus infection among the HIV seropositive patients provided a clear insight in identifying the baseline values of demographic and behavioral factors associated with these opportunistic infections.
His effort is to understand and decipher the epidemiological prevalence pattern, socio-demographic, clinical characteristics and molecular phylogeny of Human cytomegalovirus among the infected patients of Eastern Indian population. Currently he is studying the molecular characterization of congenital rubella infection (among the pediatric population) and Chikungunya infection.
Dr. Chakraborty has trained a number of students about the essential concepts of virus research. Currently three students are registered for Ph.D. and one is doing post doctoral research under his guidance. One of his students has been awarded Ph.D. and is now doing post-doctoral work. He is the author of a large number of research papers in peer-reviewed international journals and also book chapter on the aspect of Virology.
Key Achievements
During his initial years as a scientist, Dr. Chakraborty committed
himself on learning the distribution of different opportunistic
infections prevalent among the HIV infected patient groups of
Eastern India. Furthermore, he extended the work to deduce the drug
susceptibility profile of Mycobacterium tuberculosis isolated from
HIV-infected and uninfected pulmonary tuberculosis patients which
provided some significant observations regarding the prevalence and
rise of XDR-TB and MDR-TB strains in Eastern India. His research to
apprehend the frequency of multiple herpes virus infection among the
HIV seropositive patients provided a clear insight in identifying
the baseline values of demographic and behavioural factors
associated with these opportunistic infections. Later on he has
focussed his attention to understand and decipher the infectivity
pattern, epidemiological prevalence, socio-demographic, clinical
characteristics and molecular phylogeny of Human cytomegalovirus
among different patients group in eastern India. He is also involved
in the identification and characterization of noble anti-HCMV
compounds from natural resources. Dr. Chakraborty has trained a
number of students about the essential concepts of human
cytomegalovirus research. Currently four students are registered for
Ph.D. under his guidance of whom one has already submitted his
doctoral thesis. One of his students has been awarded Ph.D. and is
now doing post-doctoral work. He is the author of a large number of
research papers in peer-reviewed international journals and also
book chapters on different aspects of Virology.
Present work details
Currently Dr. Chakraborty is working to develop a comparative
assessment of the different demographic, biochemical and
immunological parameters associated with the clinical conditions of
HCMV infection in infants and HIV1 seropositive patients for proper
diagnosis and therapeutic remedy. He intends to identify specific
predictive markers of disease occurrence after thoroughly analysing
the pattern in the expression of the different significant
parameters. The identification of these markers will help to
generate a superior defining criterion for identifying and
monitoring such cases, thereby providing a greater therapeutic
advantage to the clinicians. Furthermore suitable effort has also
been put forward to understand the role of specific immunological
pathways in the same context. He is also studying the genetic
variation among the clinical HCMV strains infecting different tissue
sites and causing different clinical manifestations.
His team is also working on in-vitro HCMV infection models to test
the potential of some isolated natural compounds as anti-viral
agents. Simultaneous studies are being carried out to understand the
mechanism of action of these selected compounds against HCMV.
A part of his team is also working to understand the epidemiology of
Chikungunya virus infections among different patient groups in
eastern India
Future prospects
Preparations are on-going to begin the molecular detection of HCMV
infection and characterization of symptoms associated with HCMV
viremia among patients undergoing renal transplantation at different
metropolis hospitals of Kolkata. In this regard he and his team
intends to analyze different host risk factors (physical,
demographic, biochemical, hematological and immunological)
associated with HCMV infection among these patients.
.
Name | Dr. Nilanjan Chakraborty |
---|---|
Designation | Scientist F |
Date of joining ICMR | 26 March 2003 |
Date of joining present post | 01 September 2014 |
Discipline | |
Division | Virus research laboratory |
Specialization | Viral disease |
Email : |
nilanjan_19@yahoo.com ,
nilanjanchakraborty@ymail.com |
Academic Qualification | |
Graduation | |
Post Graduation | M.Sc.(Botany) |
Doctoral | PhD (Microbiology). |
The core area of his research work revolves around
understanding the epidemiological, serological,
immunological and molecular perspectives of Human
Cytomegalovirus biology. His lab is dedicated to study
the current trends in HCMV infection among the different
vulnerable patient populations of Eastern India
including neonates, pregnant women, HIV infected
patients and transplant recipients.
He is interested to estimate the prevalence of anaerobic
microbiota in infected root canals and to study the
possible role of Herpesvirus in endodontic infections
He is conducting research on understanding the prevalence and molecular characterization of Rubella and Chikungunya virus infections amongst different patient's groups in Eastern India.
He is also working in the translational field to
identify and characterize anti-HCMV compounds from
natural sources.
Research associate, Department of Chemistry, University
of Kalyani, 1996-1997
Junior Research Officer, Chemical Engineering
Department, IIT, Kharagpur 1998.
Research Associate, MTCC, IMTECH, Chandigarh 1999-2000
External Expert (Scientist B grade) Biotechnology, IIT
Kharagpur, 2001
Scientist C- ICMR Virus Unit, Kolkata-2003
Scientist D- ICMR Virus Unit, Kolkata-2009
Scientist E- ICMR Virus Unit, Kolkata-2014
Intramural
Extramural
Students:
Post Doctoral fellowSRF
Sabbir Ansari
Aroni Chatterjee
Rajendra Prasad Chatterjee
Dipanwita Das
JRF