The Division of Bacteriology has multifarious functions that include isolation and identification of enteric bacteria from stool specimens collected from the hospital/community through systematic surveillance, vaccine trial studies, confirmation and serotyping of enteric bacteria such as Vibrio parahaemolyticus ,toxigenic V. cholerae, diarrhoeagenic Escherichia coli, Shigella sent by other institutions, and outbreak investigations to detect the possible etiological agents. More...

The Division of Biochemistry is focused broadly on understanding the host-pathogen relationship in molecular terms. With this goal, we address characterization of microbial proteins that are involved in pathogenesis of enteric diseases and host immune response in terms of their solution structure, biochemical and biophysical characteristics and genetic regulation by using the techniques of chromatography, spectrofluorimetry, calorimetry, confocal microscopy and molecular biology. More...

Division of Clinical Medicine has the clinical trial set up in two hospitals one at (i) Infectious Diseases Hospital with in-patient facilities for (a) diseases surveillance (b) clinical trials on diarrhoeal diseases in all age groups. We have also another set up at (ii) Dr. B. C. Roy Memorial Hospital for Children where we have out-patient facilities for (a) surveillance and (b) in-patient facilities for clinical trials for diarrheal diseases and typhoid fever in children. More...

Implementing the principles and practices of good data management (DM) is essential in any health research. In comparison to other research standards such as good clinical practices (GCP) and good laboratory practices (GLP), good DM is less appreciated and supervised by investigators. This institute being a pioneer institute in Diarrhoeal research, a separate Data Management Division has been set up in October 2008 from the innovative idea of new director with view of Good Data Management practices. More...

Epidemiology division at NICED, has been involved in research projects on epidemiology of diarrhoea - observational, intervention and operational research projects like micronutrient supplementation and albendazole administration to children and its impact on growth and diarrhoeal incidence.NICED in collaboration with International Vaccine Institute, Seoul, Korea initiated a project titled “Surveillance for typhoid fever and cholera in eastern Kolkata, West Bengal, India” in 2002, to generate accurate epidemiologic, socio-behavioral, and economics data on typhoid fever and cholera in impoverished slum area populations of eastern Kolkata in preparation for field trials of vaccines against these two diseases. More...
 

Electron microscopy at the National Institute of Cholera and Enteric Diseases started in the early 80’s with the installation of a Philips state-of-the-art transmission electron microscope, model 420T. One high vacuum evaporator (shadow caster), Polaron E6100, was also installed along with the EM. Later on one LKB Nova ultramicrotome, a LKB 7800 knifemaker , one De Vere enlarger, one JEOL JEE-400 high vacuum evaporator along with a JEOL HDT400 hydrophilic treatment apparatus were also installed. More...

The major goal of the Division of Immunology has been to study mucosal immune regulation by two proteins: porin, the major outer membrane protein of the Gram negative bacteria, Shigella dysenteriae type 1, and hemolysin (HlyA), a pore-forming toxin released by Vibrio cholerae. Our research interest covers three main aspects of mucosal immunity: Toll-like receptors (TLR)-mediated recognition of the molecule by immune cells, triggering of downstream signaling pathway upon recognition, and finally, the immune outcome elicited by the signal transduction. More...

The research work of the Division of Pathophysiology is related to the understanding of pathogenesis of different diarrhoeagenic bacteria, development of candidate vaccine, Super ORS and use of proper antibiotics against diarrhoea. The scientists of this division have been working on different projects. More...

The Division of Parasitology at NICED actively integrates research into the mechanisms of parasitic diarrheal diseases at the molecular and cellular levels with epidemiological studies. While ensuring an increasing understanding of human parasitic diseases, like amoebiasis, giardiasis, cryptosporoidis etc., this provides the foundation for further developments in screening, diagnosis and future therapeutics. To support these fundamental activities, the Department of Parasitology provides extensive research and training opportunities to graduate students and other trainees of India and abroad. More...

The Division of Virology plays a key role in the surveillance studies undertaken by the National Institute of Cholera and Enteric Diseases to understand the etiological role of different diarrhoeagenic viruses in and around Kolkata to gather information with relation to the disease burden; the Division also serves to impart training to graduate and doctoral students and staff so as to improve the human resources capable of studying diarrhoeal diseases across the country. More...

The mandate of NICED is to conduct research, services and training on diarrhoeal diseases and on HIV/AIDS