What is CHOLDInet?
CHOLDInet, conceived in March 2009 as a World Health Organization (WHO)
initiative, is a laboratory network for cholera and other diarrhoeal
infections and will be a member of the Global Task Force on Cholera
CHOLDInet operates under the patronage of the WHO Global Laboratory
Directory (GLaD) which is a support system to encourage laboratory
networks to be part of a global community of peers.
CHOLDInet will aim for the greatest geographic representation of
laboratory networks on cholera and other diarrhoeas but will strive to be
useful in cholera endemic and epidemic areas where the need is the
CHOLDInet will provide strategic advice and share expertise at the
International, regional and national levels in order to enhance local and
regional capacity for laboratory-based detection and surveillance of
cholera and other etiologies of diarrhoeal diseases.
To strengthen laboratory capacity for monitoring and rapid detection of
cholera and other causes of diarrhoeal diseases to advance the application
of control measures.
To facilitate information sharing between
laboratories working on cholera and other diarrhoeal diseases in order to
enhance diagnostic capabilities
best laboratory practices that will lead to reliable laboratory data
To establish a global reference collection and
information archive of strains and reagents
Terms of Reference
To establish, maintain and expand collaborative links between
laboratories that work on cholera and other diarrhoeal diseases with the
objective of providing an international forum for sharing information,
expertise and action.
To provide expertise to develop robust laboratory-based surveillance
systems with emphasis on how to utilize information to sufficiently reduce
the number of people affected by epidemics, especially in poverty-based
To facilitate surveillance by providing reasonable quantities of laboratory diagnostic
reagents, subject to availability and sharing best practices from both feasibility as well as
To facilitate access to a Referral Centre for identification and
confirmation of strains, serotypes and genotypes.
To provide assistance in determining antimicrobial resistance and
recommendations on alternative treatment practices.
To foster and promote research that will lead to better understanding of
the effect of global climate change on climate-sensitive diseases like
To provide expert assistance on creation of
laboratory databases and interpretation of data.
To provide a single comprehensive source of
information on cholera by developing a web-based cholera portal.
Provide guidance and protocols for evaluation of
rapid diagnostic tests for cholera.
Assist WHO with building and enhancing global
laboratory capacity for the detection and laboratory surveillance of
Vibrio cholerae, by providing training and reagent
Establish international database of molecular
characteristics of Vibrio Cholerae.
To review, update standardized reference protocols
Establish an international culture collection for
reference services and research.
NATIONAL INSTITUTE OF CHOLERA AND ENTERIC DISEASES
(INDIAN COUNCIL OF MEDICAL RESEARCH)
P-33, C.I.T. Road, Scheme-XM,
Beliaghata, Kolkata – 700 010, India
Phone: 91-33 2363 3373, 2370 1176
Fax: 91-33-2363 2398/2370 5066