National Institute of Cholera and Enteric Diseases

 
 
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ANNUAL REPORT 2002-2003

The report is split into five downloadable pdf documents

 

INDEX OF NICED ANNUAL REPORT FOR 2002-2003
 

Particulars Page No.
1. Study on hospital surveillance. 10 PDF
1.1. Hospital based surveillance system for diarrhoeal diseases. 10 PDF
2. Community based studies. 13 PDF
2.1. A rural community based longitudinal study on diarrhoeagenic Escherichia coli amongst children below 5 years. 13 PDF
2.2. An operational study on effect of zinc supplementation on reduction of diarrhoeal morbidity amongst rural children. 15 PDF
2.3. A study of the impact of albendazole on the nutritional status of children between 2-5 years of age in an urban slum of Kolkata. 17 PDF
3. Clinical studies. 18 PDF
3.1. Efficacy and safety of a sucrose based hypo-osmolar ORS in adults and older children with cholera : a clinical trial. 18 PDF
3.2. Evaluation of the role of zinc supplementation in the treatment of cholera both in children and adults. 19 PDF
4. Studies on Vibrio cholerae. 20 PDF
4.1. Preferential association of the heat-stable enterotoxin gene (stn) with environmental strains of Vibrio cholerae belonging to the O14 serogroup. 21 PDF
4.2. Molecular analsysis of V.cholerae O1 ElTor Ogawa strains isolated from cholera epidemic in Nancowry group of islands, Andaman and Nicobar. 22 PDF
4.3. Characterization of rough strains of Vibrio cholerae isolated from diarrhoea patients. 23 PDF
4.4. Study the enterotoxicity of Vibrio cholerae non-O1, non-O139 in an in-vitro rat intestinal model. 28 PDF
4.5. Studies on the structure-function relationship of Vibrio cholerae hemolysin (HlyA). 32 PDF
4.6. Morphological studies on the flagella of Vibrio cholerae. 34 PDF
4.7. Molecular regulation of intestinal folate transport under the influence of cholera toxin. 37 PDF
4.8. Studies on the status of baseline serum vibriocidal antibody level against Vibrio cholerae O1 and serogroup O139 in Calcutta community. 38 PDF
4.9. Sequential studies of Vibrio cholerae 0139 and some of its defined virulence phenotypes on intestinal pathology in rabbit ileal loop model purified protein 40 mg - haemorrhagic and cytotoxic effect. 39 PDF
5. Studies on Vibrio cholerae Phages. 40 PDF
5.1. Further application of phage typing scheme for discriminating strains of Vibrio cholerae O139. 40 PDF
5.2. Nationwide screening of phage types of V. cholerae O1 biotype ElTor. 41 PDF
5.3. Molecular analysis of Vibrio cholerae bacteriophages: cloning and sequencing of phage DNA. 42 PDF
6. Studies on Shigella species. 46 PDF
6.1. Genetic studies on virulence mechanisms of Shigella dysenteriae 1 in relation to vaccine development. 46 PDF
6.2. Molecular characterization of multi-drug resistant shigella flexneri in kolkata. 48 PDF
6.3. Antigenic recognition of Shigella dysenteriae outer membrane proteins using human convalescent sera and to evaluate their role in cell-mediated immune response in shigellosis. 48 PDF
6.4. Immunoregulatory functions of porin of Shigella dysenteriae type1. 50 PDF
7. Studies on Escherichia coli. 51 PDF
7.1. Search for Shiga toxin producing Escherichia coli including O157: H7 strains in animals, animal products and hospitalised acute diarrhea cases in Kolkata. 51 PDF
7.2. Studies on the binding of Escherichia coli heat-stable enterotoxin to intestinal epithelial cells and brush border membranes of different animals. 53 PDF
7.3. Antibiotic Resistance, Virulence genes and molecular profiles of Shiga Toxin-Producing Escherichia coli Isolated From Diverse Sources in Calcutta, India. 54 PDF
7.4. Studies to determine the role of enteroaggregative Escherichia coli (EAggEC) for causing diarrhoea with reference to its virulence properties. 58 PDF
8. Studies on other bacterial enteropathogens. 59 PDF
8.1. Mode of action of Yersinia enterocolitica heat stable enterotoxin (YSTa) in rat intestinal epithelial cell. 59 PDF
8.2. Correlation of histology with genotypes of Helicobacter pylori isolated from cases of peptic ulcer, non ulcer dyspepsia,gastric carcinoma and lymphoma Histologic special strain for Hpy1; modified giemsa, gimenez stain. 60 PDF
8.3. Environmental isolates of Aeromonas spp. harboring the cagA gene of Helicobacter pylori. 62 PDF
8.4. Differentiation of Salmonella enterica Serotype Typhi by molecular methods. 67 PDF
9. Studies on diarrhoeagenic parasites. 68 PDF
9.1. Studies on electron dense granules of E. histolytica containing collagenase activity. 68 PDF
9.2. Studies on multiple genes in Entamoeba histolytica during human collagen type I and Ca2+ interaction : Use of mRNA differential display. 70 PDF
9.3. Studies on rRNA processing in Giardia lamblia. 71 PDF
9.4. Detection and characterization of Cryptosporidium parvum by molecular biological tools. 74 PDF
10. Studies on viral pathogens. 77 PDF
10.1. Detection and molecular characterization of rotaviruses. 77 PDF
10.2. Detection and molecular characterization of human Astrovirus. 83 PDF
10.3. Detection and molecular characterization of hepatitis C virus. 87 PDF
10.4. Studies on viral hepatitis among hospitalized cases in Calcutta with special reference to hepatitis E. 90 PDF
11. Epidemic investigation. 91 PDF
11.1. Epidemic of Shigella dysenteriae type 1 in Jalpaiguri district of West Bengal. 91 PDF
11.2. Investigation of an outbreak of bacillary dysentery at Diamond Harbour, North Bengal. 91 PDF
11.3. Molecular characterization of Vibrio cholerae strains that caused outbreaks in Nancowry islands of Andaman & Nicobar. 92 PDF
11.4. Outbreak of acute gastro-enteritis in Howrah Municipality area of Howrah District, West Bengal. 94 PDF
11.5. Investigation of an outbreak of hepatitis in the area of Pragatipally of South Dum Dum Municipality. 95 PDF
11.6. Epidemic investigation of unknown fever at West Midnapur District. 97 PDF
12. HIV/AIDS related works. 103 PDF
12.1. Report of National HIV Reference Centre. 103 PDF
12.3. Distribution of HIV-1 subtypes in Eastern and Northeastern regions of India. 107 PDF
13. NICED - JICA Joint Project for prevention of emerging diarrhoeal diseases. 109 PDF
14. Activities of training and extension division. 113 PDF
14.1. Training programme conducted. 113 PDF
14.2. Summer training programme. 122 PDF
14.3. Training of WHO fellows. 122 PDF
14.4. Supply of Vibrio cholerae 01 and 0139 monoclonal antibodies to different laboratories. 123 PDF
15. Scientific conference/seminar/meeting attended by the Scientists/Research Fellows/Staff. 125 PDF
16. Training received by the scientists students. 134 PDF
17. Other activities of the scientists. 136 PDF
18. Award received by the scientists. 140 PDF
19. Publications. 142 PDF
20. Committees of the institute. 147 PDF
21. List of the Staff. 151 PDF

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