| |
Particulars |
Page No. |
| 1. |
Study on hospital
surveillance. |
10 |
 1.1. |
Hospital based surveillance system for
diarrhoeal diseases. |
10,
12 |
| 2. |
Community based studies. |
13 |
|
2.1. |
A rural community based longitudinal study on
diarrhoeagenic Escherichia coli amongst children below 5 years. |
13 |
|
2.2. |
Impact of zinc supplementation on incidence of
diarrhoea and growth pattern among low birth weight infants in an urban
slum. |
14,
15, 16,
17 |
|
2.3. |
A prospective study of gender bias in health
care practices with special reference to childhood diarrhoea, acute
respiratory infections and protein energy malnutrition. |
18 |
| 3. |
Clinical studies.
|
19 |
|
3.1. |
Efficacy and safety of a sucrose based hypo-osmolar
ORS solution in adults and older children with cholera : a clinical trial. |
19 |
|
3.2. |
Evaluation of the role of zinc supplementation
in the treatment of cholera both in children and adults. |
20 |
| 4. |
Studies on
Vibrio cholerae O1 and O139. |
21 |
|
4.1. |
Molecular epidemiology of cholera in India. |
22 |
|
4.2. |
Characterization of rough strains of Vibrio
cholerae isolated from diarrhoea patients. |
23,
24, 25,
26, 27 |
|
4.3. |
Detection and analysis of mutations in gyrA
and parC genes associated with fluroquinolone resistance among clinical
strains of Vibrio cholerae and Vibrio parahaemolyticus. |
28 |
|
4.4. |
Study the role of plasmids in adherence
mechanism of V.cholerae nonO1, nonO139. |
28,
29 |
|
4.5. |
Studies on the structure-function relationship
of Vibrio cholerae hemolysin (HlyA). |
30 |
|
4.6. |
Morphological studies on the flagella of
Vibrio cholerae. |
31 |
|
4.7. |
Molecular regulation of intestinal folate transport under the influence of cholera toxin. |
33,
34 |
|
4.8. |
Studies on the status of baseline serum
vibriocidal antibody level against Vibrio cholerae O1 and serogroup O139
in Calcutta community. |
35,
36 |
| 5. |
Studies on Vibrio
cholerae Phages. |
37 |
|
5.1. |
Evaluation of new phage typing scheme for
V.cholerae O1 biotype ElTor strains. |
33 |
|
5.2. |
Search for newer phages to develop a typing
scheme for V.cholerae non-O1 (O139). |
37 |
|
5.3. |
Molecular analysis of Vibrio cholerae
bacteriophages: cloning and sequencing of Phage DNA. |
38 |
| 6. |
Studies on Shigella
species. |
43 |
|
6.1. |
Genetic studies on virulence mechanisms of
Shigella dysenteriae 1 in relation to vaccine development. |
43 |
|
6.2. |
Molecular characterization of multi-drug
resistant shigella flexneri in kolkata. |
44 |
|
6.3. |
Antigenic recognition of Shigella
dysenteriae outer membrane proteins using human convalescent sera and
to evaluate their role in cell-mediated immune response in shigellosis. |
45 |
|
6.4. |
Immunoregulatory functions of porin of
Shigella dysenteriae type 1. |
46 |
| 7. |
Studies on
Escherichia coli. |
48 |
|
7.1. |
Studies to determine the role of
enteroaggregative Escherichia coli for causing diarrhoea with
special reference to its virulence properties. |
48 |
|
7.2. |
Search for Shiga toxin producing Escherichia
coli (STEC) including O157:H7 strains in animals products, hospitalized
bloody diarrhoea cases and amongst the healthy human population in a
defined community. |
49 |
|
7.3. |
Studies on the binding of Escherichia coli
heat-stable enterotoxin to intestinal epithelial cells and brush border
membranes of different animals. |
50,
51 |
| 8. |
Studies on other
bacterial enteropathogens. |
52 |
|
8.1. |
Mode of action of Yersinia enterocolitica
heat stable enterotoxin (YSTa) in rat intestinal epithelial cell. |
52 |
|
8.2. |
Correlation of histology with genotypes of
Helicobacter pylori isolated from cases of peptic ulcer, non ulcer
dyspepsia,gastric carcinoma and lymphoma. |
53 |
|
8.3. |
Differentiation of Salmonella enterica
serotype Typhi by molecular methods. |
54 |
| 9. |
Studies on
diarrhoeagenic parasites. |
55 |
|
9.1. |
Studies on electron dense granules of E.
histolytica containing collagenase activity. |
55 |
|
9.1. |
Studies on electron dense granules of E.
histolytica containing collagenase activity. |
56 |
|
9.3. |
Studies on rRNA processing in Giardia
lamblia. |
58,
59, 60,
61 |
|
9.4. |
Detection and characterization of
Cryptosporidium parvum by molecular biological tools. |
62 |
| 10. |
Studies On Viral
Enteropathogens. |
63,
64, 65 |
|
10.1. |
Detection and molecular characterization of
rotaviruses. |
65 |
|
10.2. |
Detection and molecular characterization of
human caliciviruses and astrovirus. |
66,
67 |
|
10.3. |
Molecular characterization of hepatitis C
virus. |
68 |
| 11. |
Investigations Of Outbreaks. |
69 |
|
11.1. |
Report of investigation of outbreak of unknown
fever at Siliguri, West Bengal. |
69 |
|
11.2. |
Investigation of an outbreak of acute
diarrhoeal diseases in a part of district Sarguja in Chhattisgarh. |
70 |
|
11.3. |
Report of investigation of outbreak of
diarrhoeal disease at Chindwara district of Madhya Pradesh and Sarguja
district of Chattisgarh states. |
71 |
|
11.4. |
Investigation of hepatitis outbreak at Rishra
municipal area, Hooghly district, West Bengal. |
72,
73 |
|
11.5. |
Investigation of hepatitis outbreak at Kulti
municipal area, Bardhaman District, West Bengal. |
74,
75 |
| 12. |
Report Of The National
HIV Reference Centre. |
76,
77 |
| 13. |
NICED Project For
Prevention Of Emerging Diarrhoeal Diseases. |
78,
79, 80,
81 |
| 14. |
Activities of Training
and Extension Division. |
82 |
|
14.1. |
Workshops/training Programmes conducted. |
82 |
|
14.1.1. |
ICMR-NICED Training programme on isolation,
identification and antimicrobial resistance monitoring of enteric
pathogens. |
82 |
|
14.1.2. |
Workshop on ethical issues in biomedical
research. |
83 |
|
14.1.3. |
NICED/NICD review cum refresher course for
nodal officers of the Eastern States and districts under NSPCD. |
84 |
|
14.1.4. |
ICMR-WHO workshop on use of Information
Technology in Bio-medical Research. |
84 |
|
14.1.5. |
JICA-NICED training course on molecular
epidemiology of diarrheal diseases with special reference to cholera. |
84 |
|
14.1.6. |
NACO/NICED training course on external quality
assessment scheme for HIV testing (2nd phase). |
85 |
|
14.1.7. |
Training programme on Immunization
Strengthening Project. |
85 |
|
14.1.8. |
Other Training and Teaching Programmes. |
85 |
|
14.1.9. |
Guest lectures. |
86 |
| 15. |
Awards/Honours Received
By The Scientists/Students. |
87 |
| 16. |
(a) Training received by
the Staff. |
89, 88 |
|
(b) Training received by
the students. |
89 |
| 17. |
Scientific
Conference/Seminar/Meeting Attended By The Scientists/Research
Fellows/Staff. |
90,
91, 100, 101,
102 |
| 18. |
List Of Publications.
|
103,
104,
105 |
| 19. |
Committees of the
Institute. |
106,
107, 108,
109, 110,
111 |
| 20. |
List of the Staff. |
112,
113, 114,
115, 116 |
|
|
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