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Particulars |
Page No. |
| 1. |
Study on Hospital Surveillancedy. |
1 |
|
1.1. |
Hospital based surveillance system for diarrhoeal
diseases. |
2 |
| 2 |
Community Based Studies. |
4 |
| 2.1. |
Impact of zinc supplementation in reducing diarrhoeal
morbidity amongst under five children : a community based intervention
study. |
5 |
| 2.2. |
Impact of lactation counselling on exclusive breast feeding
among rural mothers : An operational research. |
7 |
| 2.3. |
A rural community based longitudinal study on
diarrhoeagenic Escherichia coli amongst children below 5 years. |
9 |
| 2.4. |
Impact of zinc supplementation on incidence of diarrhoea
and growth pattern among low birth weight infants of an urban slum. |
10 |
| 2.5. |
A case control study on risk factors of dehydrating
diarrhoea in children. |
10 |
| 3. |
Clinical Studies. |
11 |
| 3.1 |
Impact of supplementation of zinc, zinc and vitamin A and
combination of micronutrients and vitamins on acute watery diarrhoeal in
mild to moderately malnourished children. |
12 |
| 3.2 |
Efficacy and safety of a sucrose based hypoosmolar ORS
solution in adults and older children with cholera : a clinical trial. |
13 |
| 3.3 |
Evaluation of comparative efficacy of Erythromycin and
Azithromycin in the treatment of cholera in children. |
14 |
| 4. |
Studies on Vibrio cholerae
o1 and O139. |
15 |
| 4.1. |
Emergence of Fluoroquinolone Resistant Strains of Vibrio
cholerae O1 Biotype ElTor among Hospitalized Patients with Cholera
in Calcutta. |
16 |
| 4.2. |
Emergence of Vibrio cholerae O1 Biotype ElTor
serotype Inaba from the prevailing O1 Ogawa serotype strains in India. |
18 |
| 4.3. |
Characterization of rough strains of Vibrio cholerae
isolated from diarrhea patients. |
22 |
| 4.4. |
Virulence Genes in Environmental Strains of Vibrio
cholerae. |
23 |
| 4.5. |
Study the role of plasmids in adherence mechanism of
V.cholerae non-O1, non-O139. |
26 |
| 4.6. |
Studies on structure function relationship of Vibrio
cholerae haemolysin. |
27 |
| 4.7. |
Isolation of N-acetyl-D-glucosamine specific hemagglutin
receptor of Vibrio cholerae O1 in chicken erythrocyte membranes. |
27 |
| 4.8. |
Vibriocidal studies on the status of vibriocidal serum
bricidal antibody level against Vibrio cholerae O1 and serogroup
O139 in Calcutta community. |
29 |
| 4.9. |
Sequential studies of Vibrio cholerae O139 and some
of its defined virulence phenotypes on intestinal pathology in rabbit
ileal loop model. |
29 |
| 4.10. |
Morphological studies on the flagella of Vibrio cholerae. |
30 |
| 5. |
Studies on Vibrio cholerae phages
V.cholerae O139. |
31 |
| 5.1. |
Further application of phage typing scheme for discriminating strains
of V.cholerae O139. |
32 |
| 5.2. |
Nationwide screening of phage types of V.cholerae 01 biotype
Eltor. |
32 |
| 5.3. |
Molecular analysis of Vibrio cholerae bacteriophages: cloning
and sequencing of phage DNA. |
32 |
| 5.4. |
Morphological and genomic characterization of vibriophages by electron
microscopy. |
33 |
| 6. |
Studies on Shigella species. |
35 |
| 6.1. |
Antigenic recognition of Shigella dysenteriae outer membrane proteins
using human convalescent sera and to evaluate their role in
cell-mediated immune response in Shigellosis. |
36 |
| 6.2. |
Immunoregulatory functions of porin of Shigella dysenteriae
type 1. |
37 |
| 6.3. |
Genetic studies on virulence mechanisms of Shigella dysenteriae
1 in relation to vaccine development. |
38 |
| 6.4. |
Molecular characterization of multi-drug resistant Shigella
flexneri in Calcutta. |
39 |
| 7. |
Studies on Escherichia coli. |
40 |
| 7.1. |
Studies to determine the role of enteroaggregative Eschrichia coli
(EAggEC) for causing diarrhoea with reference to its virulence
properties. |
41 |
| 7.2. |
Search for Shiga toxin producing Escherichia coli including
O157: H7 strains in animals, animal products and hospitalised acute
diarrhea cases in Calcutta. |
41 |
| 7.3. |
Studies on the binding of Escherichia coli heat-stable
enterotoxin to the intestinal epithelial cells and brush border
membranes of different animals. |
42 |
| 8. |
Studies on other bacterial pathogens. |
44 |
| 8.1. |
Differentiation of Salmonella typhi by molecular methods. |
45 |
| 8.2. |
Regulation of expression of bacteriophage MB78 genes : A molecular
app. |
45 |
| 8.3. |
Mode of action of Yersinia enterocolitica heat stable
enterotoxin (YSTa) in rat intestinal epithelial cell. |
47 |
| 8.4. |
Search for virulence traits and determination of the mechanism of
pathogenecity of Klebsiella pneumoniae isolated from childhood
diarrhoea cases. |
47 |
| 8.5. |
Correlation of histology with genotypes of Helicobacter pylori
isolated from cases of peptic ulcer, non-ulcer dyspepsia, gastric
carcinoma and lymphoma. |
48 |
| 9. |
Studies on E.histolytica. |
51 |
| 9.1. |
Studies on electron dense granules of E.histolytica containing
collagenase activity. |
51 |
| 9.2. |
Studies on multiple genes in Entamoeba histolytica during human
collagen type I and Ca2+ interaction : Use of mRNA differential display. |
52 |
| 10. |
Studies on rotavirus. |
54 |
| 10.1. |
Molecular characterization of the VP7 genes of rotavirus isolated from
the clinical samples, Calcutta, India. |
54 |
| 10.2. |
Detection and molecular characterization of rotaviruses. |
55 |
| 11. |
Investigations of outbreaks of diarrhoeal
diseases. |
58 |
| 11.1. |
Investigation of outbreak of acute diarrhea in the brickfield area of
Akra Fatak Calcutta. |
58 |
| 11.2. |
Visit to Bhuj, Gujarat to investigate any impending Diarrhoeal disease
outbreak following recent earthquake disaster. |
59 |
| 11.3. |
Investigation of V.cholerae O139 outbreak at Baishnabghata,
Patuli, Kolkata. |
60 |
| 11.4. |
Concomitant Infection of Enterotoxigenic Escherichia coli in an
Outbreak of Cholera Caused by Vibrio cholerae O1 and O139 in
Ahmedabad. |
61 |
| 12. |
Report of the National HIV Reference Centre. |
64 |
| 13. |
JICA-NICED project for prevention of emerging
diarrhoeal diseases. |
67 |
| 14. |
Activities of training and extension
division. |
69 |
| 14.1. |
NACO Expert Group Meeting on Quality Assurance of HIV Testing. |
69 |
| 14.2. |
JICA-NICED Domestic Training Programme on "Molecular Epidemiology of
Diarrhoeal Diseases with Special Reference to Cholerae". |
69 |
| 14.3. |
Other Training and Teaching Programmes. |
69 |
| 14.4. |
Guest lectures. |
70 |
| 14.5. |
Training of W.H.O. Fellow. |
70 |
| 14.6. |
Foreign scientist received training in the Institute. |
70 |
| 15. |
Scientific Conference/seminars/meeting
attended by the scientists/research fellows Training received by the
scientists in abroad. |
71 |
| 16. |
Award/honour received by the scientists. |
80 |
| 17. |
Other activities by the scientists. |
81 |
| 18. |
Committee of the institute. |
82 |
| 19. |
List of publications. |
85 |
| 20. |
Staff list. |
90 |
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