|
Particulars |
Page No. |
| 1. |
Hospital Surveillance
Study. |
1 |
|
1.1. |
Hospital based surveillance system for
diarrhoeal diseases. |
1 |
| 2. |
Community Studies. |
2 |
| 2.1. |
Impact of zinc supplementation in reducing
diarrhoeal morbidity amongst under five children : a community based
intervention study. |
2 |
| 2.2. |
Impact of zinc supplementation on incidence of
diarrhoea and growth pattern among low birth weight infants of an urban
slum. |
5 |
| 2.3. |
A rural community based longitudinal study on
diarrhoeagenic Escherichia coli amongst children below 5 years. |
7 |
| 2.4. |
Epidemiological study of Typhoid Fever in a
rural community of West Bengal. |
8 |
| 2.5. |
Impact of lactation counselling on exclusive
breast feeding among rural mothers : An operational research. |
8 |
| 3. |
Studies on Vibrio
cholerae and Vibrio Phages. |
10 |
| 3.1. |
Molecular epidemiology of cholera in India. |
10 |
| 3.2. |
Study the role of plasmids in adherence
mechanism of V.cholerae non-O1, non-O139. |
11 |
| 3.3. |
Isolation and characterization of the chicken
erythrocytes receptor for N-acetyl-D-glucosamine specific hemagglutinin/adhesin. |
11 |
| 3.4. |
Studies on the structure function relationship
of Vibrio cholerae hemolysin. |
12 |
| 3.5. |
Sequential studies of Vibrio cholerae O139 and
some of its defined virulence phenotypes on intestinal pathology in
rabbit ileal loop model. |
13 |
| 3.6. |
Evaluation of new phage typing scheme for V.cholerae
O1 biotype ElTor strains. |
13 |
| 3.7. |
Search for newer phages to develop a phage typing scheme
for V.cholerae O139. |
14 |
| 3.8. |
Morphological and genomic characterization of
vibriophages by electron microscopy. |
15 |
| 3.9. |
Bacteriophage MB78 : Regulation of gene
expression. |
15 |
| 3.10. |
Comparative analysis of cytotoxin, hemolysin,
hemagglutinin and exocellular enzymes among clinical and environmental
isolates of Vibrio cholerae O139 and non-O1, non-O139. |
17 |
| 4. |
Studies on Shigella
species. |
17 |
| 4.1. |
Immunoregulatory functions of porin of
Shigella dysenteriae type 1. |
17 |
| 4.2. |
Antigenic recognition of Shigella
dysenteriae outer membrane proteins using human convalescent sera
and to evaluate their role in cell mediated immune response in
Shigellosis. |
18 |
| 4.3. |
Genetic studies on virulence mechanisms of
Shigella dysenteriae 1 in relation to vaccine development. |
18 |
| 4.4. |
Studies on possible virulence factors in
Shigella species. |
19 |
| 4.5. |
Evaluation of DNA amplification method with
conventional microbiological techniques for detection of Shigella
and EIEC in stool samples from children with acute diarrhoea. |
20 |
| 4.6. |
Molecular characterization of multi-drug
resistant Shigella flexneri in Calcutta. |
20 |
| 5. |
Clinical Studies. |
21 |
| 5.1. |
Efficacy and safety of a sucrose based
hypoosmolar ORS solution in adults and older children with cholera : a
clinical trial. |
21 |
| 5.2. |
Impact of supplementation of zinc, zinc and
vitamin A and combination of micronutrients and vitamins on acute watery
diarrhoeal in mild to moderately malnourished children. |
21 |
| 5.3. |
Evaluation of comparative efficacy of
Erythromycin and Azithromycin in the treatment of cholera in children. |
23 |
| 6. |
Studies on other
Enteric Organism. |
23 |
| 6.1. |
Search for virulence traits and determination
of the mechanism of pathogenicity of Klebsiella pneumoniae
isolated from childhood diarrhoea cases. |
23 |
| 6.2. |
Studies on the role of enteroaggregative
Escherichia coli (EAggEC) as a cause of diarrhoea with reference to
its virulence properties. |
24 |
| 6.3. |
Search for Shiga toxin producing
Escherichia coli including O157 : H7 strains in animals, animal
products and hospitalized acute diarrhoea cases in Calcutta. |
24 |
| 6.4. |
Studies on the binding of Escherichia coli
heat-stable enterotoxin to intestinal epithelial cells and brush border
membranes of different animals. |
25 |
| 6.5. |
Molecular characterization of Vibrio
parahaemolyticus O3:K6 strains harboring the gene tdh,
isolated from clinical samples in Calcutta. |
26 |
| 6.6. |
Differentiation of Salmonella typhi by
molecular methods. |
27 |
| 6.7. |
Correlation of histology with genotypes of
Helicobacter pylori isolated from cases of Peptic ulcer,Non ulcer
dyspepsia,Gastric carcinoma and Lymphoma. |
28 |
| 7. |
Studies on Parasitic
Diarrhoea. |
28 |
| 7.1. |
Studies on electron dense granules of
E.histolytica containing collagenase activity. |
28 |
| 7.2. |
Studies on multiple genes in Entamoeba
histolytica during human collagen type I and Ca2+ interaction : Use
of mRNA differential display. |
29 |
| 8. |
Studies on Viral
Diseases. |
29 |
| 8.1. |
Nucleotide Sequence of VP7 gene of rotavirus
detected from Calcutta. |
29 |
| 8.2. |
Detection and molecular characterization of
Rotaviruses. |
30 |
| 8.3. |
Comparative genome analysis of human
Rotaviruses prevalent in India (DBT). |
31 |
| 8.4. |
National HIV Reference Centre. |
32 |
| 9. |
JICA/NICED Project
for Prevention of Emerging Diarrhoeal Diseases. |
34 |
| 10. |
Training and
Extension. |
35 |
| 10.1. |
Training Course on Antimicrobial Resistance
Monitoring. |
35 |
| 10.2. |
Training course on clinical management of
cholera and other diarrhoeal diseases. |
35 |
| 10.3. |
Others. |
35 |
| 10.4. |
Guest lectures. |
36 |
| 10.5. |
Training of W.H.O. Fellow. |
36 |
| 10.6. |
Training/visit of the Institute staff. |
37 |
| 10.7. |
Honours/Awards to the Institute Staff. |
37 |
| 10.8. |
Ph.D. award to the Institute scholars. |
37 |
| 10.9. |
Other activities of the Institute staff. |
38 |
| 11. |
National Science Day
Celebration, 2000. |
41 |
| 12. |
Brain storming
session on Helicobacter pylori. |
41 |
| 13. |
Referral Service from
Vibrio Phage Reference Laboratory. |
42 |
| 14. |
Scientific
Conferences/Seminars/Meetings attended by the Scientists/Research
Fellows. |
43 |
| 15. |
List of Publications. |
56 |
| 16. |
Staff. |
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